Talk:Diphenhydramine

This is the talk page for discussing improvements to the Diphenhydramine article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Archives: 1: 60 days

Pharmacology High‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
High	This article has been rated as High-importance on the project's importance scale.

Chemicals Mid‑importance

	This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Psychoactive and Recreational Drugs (defunct)

This article is within the scope of WikiProject Psychoactive and Recreational Drugs, a project which is currently considered to be defunct.Psychoactive and Recreational DrugsWikipedia:WikiProject Psychoactive and Recreational DrugsTemplate:WikiProject Psychoactive and Recreational DrugsPsychoactive and Recreational Drugs articles

Medicine Mid‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Altered States of Consciousness Low‑importance

	This article is within the scope of WikiProject Altered States of Consciousness, a collaborative effort to improve the coverage of altered states of consciousness on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Altered States of ConsciousnessWikipedia:WikiProject Altered States of ConsciousnessTemplate:WikiProject Altered States of ConsciousnessAltered States of Consciousness articles
Low	This article has been rated as Low-importance on the project's importance scale.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Diphenhydramine.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Using PMID: 23357028 (Citatin [61]) as a source for potentially wrong (in the case of Diphenhydramine) many listed pharmacological binding affinities in this wiki

I think this is problematic issue as this citation for this paper, (PMID: 23357028) upon inspection, it is simply reviewing an extremely wide variety of antihistamanergic drugs, in the paper no actual claims are made that diphenhydramine has any direct activity at dopamine 2 receptors or 5-HT2A receptors, i think any entry on this wiki page using this paper as a citation should be reviewed. Databoose43 (talk) 11:01, 4 February 2024 (UTC)[reply]

Anxiety

I used Diphenhydramine for anxiety for a long time, and it works, although its not approved to treat Anxiety. Of course, this is an off label use, but it works. My friends also tell me how much it helped them, so I added a sub section under Medical uses for this. There are many other anti histamines, and they are meant to treat anxiety. For example Hydroxyzine. But Hydroxyzine requires a prescription, while Benadryl can be purchased without a prescription. A prescription can be difficult to get sometimes, and when you need something quick and easy to get to help you relax, Benadryl is a good temporary choice. I was hoping if somebody can please help improve the article by adding more details about Diphenhydramine's ability to help with Anxiety. It also has antidepressant properties, which is mentioned somewhere in the article, but there's not enough details it seems.

For now, I only added the anxiety sub section. Noam Atadgy (talk) 02:41, 8 November 2024 (UTC)[reply]